The aim of this study was to provide an overview of the risk factors for acute myocardial infarction in patients attending Tripoli Medical Centre, Libya. Records were reviewed for 622 patients with a mean age of 58.3 (SD 12.9) years. Diabetes mellitus (48.2%), hypertension (35.7%) and smoking (50.6%) were among the risk factors reported. There were 110 patients (17.7%) who died during hospitalization, mainly suffering cardiogenic shock (48.0%). The rate of use of thrombolytic therapy was low in patients who were female (40.4% versus 58.4% for males), older age (31.6% for those > 85 years versus 63.3% for patients < 55 years), diabetics (45.3% versus 62.0% for non-diabetic patients) and hypertensives (47.3% versus 57.8% for non-hypertensive patients). Prevention strategies should be implemented in order to improve the long-term prognosis and decrease overall morbidity and mortality from coronary artery disease in Libyan patients. arabic 20 English 112
Hawa Juma El-Shareif(4-2012)

Fungi are a huge source of unexplored bioactive compounds. Owing to their biological activities, several fungi have shown commercial application in the health industry. Tuber aestivum Vittad. is one such edible fungi with an immense scope for practical biological applications. In the present study, the anti-angiogenic activity of petroleum ether and ethanol extracts of T. aestivum was investigated using the chick chorioallantoic membrane assay and compared to the positive controls silibinin and lenalidomide. Both the extracts showed a dose-dependent anti-angiogenic response. The extracts were also assessed for their anti-inflammatory potential by lipoxygenase-inhibition assay. The IC50 values for LOX inhibition assay, computed by the Boltzmann plot, were 368.5, 147.3 and 40.2 μg/mL, for the petroleum ether extract, ethanol extract, and the positive control ascorbic acid, respectively. The ethanol extract of T. aestivum showed superior anti-angiogenic and anti-inflammatory activity than the petroleum ether extract. Compositional investigation of the extracts by GC–MS revealed the presence of various bioactive compounds. The compounds were correlated to their anti-angiogenic and antiinflammatory activity based on a meticulous literature search. arabic 25 English 145
Sandesh J. Marathe, Abdulla Bashein, (1-2020)

Background and objectives: Allergic rhinitis is common association to asthma according to worldwide studies which showed that control of allergic rhinitis improves in turn asthma symptoms so we have conducted this study looking for the percent of allergic rhinitis in Libyan asthmatic children who were attending regular follow up in asthma clinic of Tripoli children hospital over period of one year (2008). Methods: This study was conducted by asking children’s parents using questionnaire composed of directly answered questions (yes or no) if their children got attacks of rhinorrhea, nasal itching and sneezing around certain times of the year (spring and autumn). Results: Conclusively we found that the incidence of allergic rhinitis in asthmatic Libyan children was 36.6%. Conclusion: allergic rhinitis is common with asthma, and it needs to be put in consideration in any asthma patient and treated accordingly. Cite this article: Elzigallai O, Alrabty H. Study of the Association between Allergic Rhinitis arabic 12 English 82
Hisham Alrabty, Ola Mahmoud Alzigallei(3-2020)