Dosimetry characterization and the evaluation of kinetics parameters of trapping states of Mg-doped ZnO phosphors synthesized by Sol-Gel technique. The thermoluminescence response of Mg-doped ZnO samples showed a linear response when exposed to X-ray radiation and the optimum annealing condition was 400oC/4h for the three concentrations. A broad-shaped TL glow curve with an upper bound of 270 °C, which shifts to lower temperatures with increasing dose, indicating that general order (GO) kinetics thermoluminescence processes are involved. We conclude that the ZnO doped Mg phosphors under study are promises to develop dosimeters for high radiation dose measurements. Kinetic parameters, such as activation energy (E), frequency factor (s), and order of kinematic order (b), were estimated by the Glow Curve Deconvolution (GCD) method. ZnO:Mg phosphor has a great potential as a dosimeter for monitoring in the fields of ionizing radiation. arabic 9 English 49
Fawzeia Khamis, , (1-2021)

Accumulating evidence indicates the role of endocrine disruptor bisphenol A (BPA) in many pathological conditions. Histone deacetylase (HDAC) inhibition has potential for the treatment of many diseases/abnormalities. Using a mouse BPA exposure model, this study investigated the hepatoprotective effects of the Food and Drug Administration–approved HDAC2 inhibitor valproic acid (VPA) against BPA-induced liver pathology. We randomly divided 30 adult male Swiss albino mice (8 weeks old; N = 6) into five groups: group 1, no treatment (sham control (SC)); group 2, only oral sterile corn oil (vehicle control (VC)); group 3, 4 mg/kg/day of oral BPA (single dose (BPA group)); group 4, 0.4% oral VPA (VPA group); and group 5, oral BPA + VPA (BPA + VPA group). At the age of 10 weeks, the mice were euthanized for biochemical and histological examinations. BPA promoted a significant decrease in the body weight (BW), an increase in the liver weight, and a significant increase in the levels of liver damage markers aspartate aminotransferase and alanine aminotransferase in the BPA group compared to SC, as well as pathological changes in liver tissue. We also found an increase in the rate of apoptosis among hepatocytes. In addition, BPA significantly increased the levels of oxidative stress indices, malondialdehyde, and protein carbonylation but decreased the levels of reduced glutathione (GSH) in the BPA group compared to SC. In contrast, treatment with the HDAC2 inhibitor VPA significantly attenuated liver pathology, oxidative stress, and apoptosis and also enhanced GSH levels in VPA group and BPA + VPA group. The HDAC2 inhibitor VPA protects mice against BPA-induced liver pathology, likely by inhibiting oxidative stress and enhancing the levels of antioxidant-reduced GSH.
Mohamed A. Al-Griw, Zaynab Osama Alshibani, Rabia Omar abdullah Alghazeer, Mohamed Elhensheri, Refaat. M. Tabagh, Areej A. Eskandrani, Wafa S. Alansari, Mahmoud M. Habibulla, Ghalia Shamlan(6-2022)

Abstract The study area is located in and around Umm Ar Razam village, about 50 Km east of Darnah city, north-eastern Libya. In this study many claystone sections were studied. These claystones belong to the lowermost part of Al Faidiyah formation of Upper Oligocene – Lower Miocene age. The studied sections consist of claystone beds ranging in thickness about 10 meters. These bentonitic clays are generally grey to greenish grey in colour, with popcorn – like appearance. They have a waxy character and are exposed sporadically in this area as isolated outcrops. They might be deposited in lagoonal, lacustrine or shallow marine environment. The main purpose of this thesis is to study the origin and to evaluate the Umm Ar Razam bentonitic clays. For example, lithology, mineralogy, the chemical composition, crystal forms and habits, physical properties, industrial uses and treatment will be investigated. The Results showed that these clays consist of the minerals Na- montmorillonite, Kaolinite, and Illite. Non – clay minerals includes quartz, calcite, dolomite, gypsum, halite, muscovite, rutile, sanidine, and tridymite. Moreover, clay mineral fraction studies using the different techniques showed that these bentonitic clays were formed due to in situ alteration of volcanic ash in subaquous environment. Evidences for such an occurrence include mineralogical evidence as the existence of high temperature minerals as sanidine, rutile, and tridymite. The existence of unaltered volcanic ash as seen from SEM photomicrographs also supports this origin. Furthermore, XRF results showed downward depletion of silica right below these bentonitic clays 6 in calcarenite beds of Al Abraq formation. XRF results also showed that the Umm Ar Razam bentonites are in accordance with the American bentonites and the parent material of such bentonites came from basic volcanic ash materials. In addition, the viscosity and the filtration of Umm Ar Razam bentonite is nearly identical with the international bentonite by adding (Soda Ash) and (Na2 SiO3 ) with special treatment method. The cost of the Enhanced Umm Ar Razam bentonite is less than of the imported bentonite cost. Based on the physical and chemical properties these bentonites can be used in many industries especially as building materials and drilling fluids.
فيصل عياد أبو سهمين (2009)